10-man PSG claim Chelsea revenge

Posted On Jan 11 2020 by

first_img0Shares0000LONDON, March 12- Thiago Silva scored a sensational extra-time header as 10-man Paris Saint-Germain knocked Chelsea out of the Champions League after an electrifying 2-2 draw at Stamford Bridge on Wednesday.PSG had talisman Zlatan Ibrahimovic sent off in the first half and fell behind to a Gary Cahill goal with nine minutes remaining, only for Chelsea old boy David Luiz to take the tie to extra time with an emphatic 86th-minute header. Silva appeared to have gifted Chelsea a place in the last eight after conceding a penalty for handball that Eden Hazard converted, but the PSG captain scored with six minutes of the game remaining to send Laurent Blanc’s side through on away goals after a 3-3 aggregate draw.The irony of the scoreline will not have been lost on PSG, who were eliminated by Chelsea on away goals in last season’s quarter-finals after another 3-3 draw, but their breakthrough victory was richly deserved after a mature and resolute display on a tense and fractious night.The French champions’ dreams of an unprecedented quadruple remain intact, while Jose Mourinho will have to wait at least another season for an opportunity to win the Champions League with his beloved Chelsea.It was a game almost totally devoid of incident until a moment of controversy in the 32nd minute that thrust referee Bjorn Kuipers beneath the spotlight beams.After a PSG move broke down, Ibrahimovic showed a shade too much eagerness to regain possession by sliding in on Oscar, but although he caught the Brazilian on the ankle, both players were equally committed to the challenge and the red card that followed felt excessive.PSG were, understandably, rattled, with Thiago Motta booked for dissent, and Chelsea threatened to capitalise, with Diego Costa denied a penalty despite clearly being caught on the lower leg by Edinson Cavani.But PSG kept their shape well and shortly before the hour they came within inches of going ahead.– Verratti incurs suspension –A brisk move down the centre of the pitch involving Marco Verratti and Javier Pastore saw the latter release Cavani, who neatly skirted Thibaut Courtois, only to hit the left-hand post from an angle with the goal at his mercy.PSG continued to press, Cahill blocking from Blaise Matuidi and Courtois saving from Pastore, and with the tie on a knife-edge, tempers began to fray.Costa was booked for a dangerous late challenge on Silva and in the aftermath, Luiz received a yellow card for trying to claim he had been headbutted by the Chelsea striker.Moments later Verratti, too, saw yellow, for catching Hazard, ruling him out of the first leg of the quarter-final.After Sirigu had thwarted Ramires at his near post, Chelsea broke the deadlock from a corner when Costa took an air shot and the ball fell kindly for Cahill to slam home.But after PSG substitute Ezequiel Lavezzi had seen a header saved by Sirigu, his corner allowed Luiz to take the tie to extra time with a thumping near-post header that cannoned into the net via the crossbar.Silva’s recent performances suggested a return to his optimum level, but he was guilty of a rush of blood to the head early in extra time when he challenged Kurt Zouma for a high ball with his arms way above his head.Replays were inconclusive as to whether he actually made contact with the ball, but Hazard made no mistake from the spot.Courtois saved brilliantly from a Luiz free-kick and a Silva header, but the PSG captain had the final say with a goal that settled a breathless and dizzying contest and took the visitors into a new dimension.0Shares0000(Visited 1 times, 1 visits today)last_img read more


Carson mayor won’t seek state seat

Posted On Jan 3 2020 by

first_imgASSEMBLY: Dear instead backs Furutani. Observers say funding and endorsement shortfalls prompted the move. By Gene Maddaus STAFF WRITER After flirting with the idea for several months, Carson Mayor Jim Dear has decided not to run for the 55th District Assembly seat. Dear’s endorsement gives the Furutani campaign a presence in Carson, which is the central city in the district. But his withdrawal will also help Gipson, who will now be the only Carson candidate in the race. “If Jim had been in the race, it would have made virtually no difference,” said Fred Huebscher, a campaign consultant for Dear. “In some places, Jim might hurt Gipson, and in other places he would hurt Furutani.” Dear’s next campaign will be fought in court. A recall petition has been pending against him since March, when the county registrar-recorder ruled that the pro-recall group had fallen 86 signatures shy of the number required to force a recall election. The group, Carson Citizens for Reform, protested, arguing that several hundred signatures were improperly disqualified. City Clerk Helen Kawagoe has asked a judge to sort out the matter. In legal filings, Dear’s attorney has argued that the registrar’s ruling was binding and not subject to appeal. Carson Citizens for Reform, led by former Councilwoman Vera Robles Dewitt, filed a response last week arguing that 868 signature withdrawal cards, which had been submitted by Dear, should be thrown out because they were not dated or witnessed by Carson residents. The group also alleges that Kawagoe – who is affectionately known at City Hall as “Mother” – may be suffering from symptoms of old age, “including regular forgetfulness, frequent inattention and distraction, impaired reasoning abilities and reduced abilities of her sight and hearing.” The group suggests that these symptoms caused her to err in rejecting certain signature challenges. When her opponent tried to make age an issue in the March election, Kawagoe accused him of age discrimination and said she was as energetic as ever. At the time she declined to disclose her age, which public records put at 80, and which CCR estimates at “in excess of 84.” “We’re obviously disappointed they would raise an issue that has no legal relevance,” said City Attorney Bill Wynder, speaking on Kawagoe’s behalf. Dewitt, who put more than $45,000 into the campaign to recall Dear, defended the claim. “We expect the clerk to do her job and make the tough calls that have to be made,” Dewitt said. “For whatever reason, she did not make this call.” No date has been set for a hearing on the merits of the case. The Assembly primary will be held Dec. 11. gene.maddaus@dailybreeze.com 160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set! Instead, he will stay in Carson to fight a recall effort that will soon be headed to the courts. Dear expressed strong interest in the Assembly race in June, when incumbent Laura Richardson was elected to Congress. He told several forums he would make a bid, and made the rounds of endorsement interviews. But several key groups – including the Association for Los Angeles Deputy Sheriffs – decided to endorse veteran pol Warren Furutani instead. “I think it had mostly to do with money,” said Patrick Furey, who is managing the campaign of Carson Councilman Mike Gipson. “He thought he was going to get some endorsements he didn’t get, and he didn’t want to put up his own money to run.” Furutani announced Monday that Dear had endorsed him. Dear did not return several calls for comment, though the campaign quoted him as saying, “Warren Furutani is clearly the most qualified candidate to represent the 55th Assembly District in Sacramento.” last_img read more


BaseLine Tap House Opens at Disney’s Hollywood Studios

Posted On Dec 21 2019 by

first_imgShare This!©DisneyRecently, Disney announced that there would be a brand new lounge introduced for Disney’s Hollywood Studios. Called BaseLine Tap House, the restaurant’s theme would be that would be a cheerful corner pub that specializes in beer and wines from California. Plus, there would be small plate options to nibble on too!Well, today, BaseLine Tap House officially opened for Guests! It can be found in the former location of the Writer’s Stop, near Sci Fi Din-In, in a brand new area of the theme park called Grand Avenue. Grand Avenue features vintage office buildings and warehouses in Downtown Los Angeles.BaseLine Tap House pays homage to the Figueroa Printing Company, which at one time was a mom-and-pop print house that once enjoyed a flourishing partnership with Disney Studios. Guests can dine inside, or if they would prefer can sit in the shade on the the terrace outside.The menu includes a Bavarian pretzel with fondue, a charcuterie board, and spiced almonds. Of course, the restaurant also includes many different beverages, including beers and wines from the Golden State of California, featuring craft ales, lagers and cider. Can’t choose which beer to choose? BaseLine Tap House features customizable beer flights, with up to 126 possible combinations of craft beers. That’s a lot of choices! There are also California wines on tap and specialty cocktails available. There are also non-alcoholic options in gourmet lemonade and soda on tap.BaseLine Tap House will be open daily beginning at 11:00 a.m.last_img read more


Auburndale baseball defeats Newman Catholic for third-straight win

Posted On Dec 20 2019 by

first_imgApaches now 4-4 in Marawood SouthBy Paul LeckerSports ReporterWAUSAU — The Auburndale baseball team won its third game in a row with an 8-1 victory over Wausau Newman Catholic in a Marawood Conference South Division game Thursday at Brockmeyer Park.The Apaches scored three runs in both the third and seventh innings to pull away.Auburndale is now 4-5 overall and 4-4 in the Marawood South, moving ahead of Newman Catholic (4-8, 4-6 Marawood South) in the conference standings.Logan Willfahrt and Colton Wright each had two this and two RBIs, and Cason Schmutzer added a pair of hits for the Apaches.Cam Ertl was the winning pitcher, striking out four in six innings.Auburndale hosts first-place Marathon on Friday at 4:45 p.m.(Hub City Times Sports Reporter Paul Lecker is also the publisher of MarshfieldAreaSports.com.)Apaches 8, Cardinals 1Auburndale 013 001 3 – 8 9Newman Catholic 001 000 0 – 1 4WP: Cam Ertl.SO: Ertl (6 inn.) 4, Colton Wright (1 inn.) 1. BB: Ertl 5, Wright 0.Top hitters: A, Logan Willfahrt 2×4, 2 RBIs; Ryan Isaacson 2 runs; Cason Schmutzer 2×4, 2 runs; Wright 2×4, 2B, 2 RBIs.Records: Auburndale 4-5, 4-4 Marawood South; Wausau Newman Catholic 4-8, 4-6 Marawood South.last_img read more


Data Management: Four Criteria for Ranking Search Effectiveness

Posted On Dec 17 2019 by

first_imgDespite the advances i nsearch technology, companies still struggle to quickly locate and retrieve information that they’re searching for.  A survey from MindMetre Research and Smartlogic estimates that 52 percent of senior managers and directors at US and major European of organizations aren’t able to quickly locate the documents and information they’re looking for because the information has been poorly or incorrectly classified.When these managers were queried about what they perceived as being an acceptable amount of time to search for data, 65 percent indicated that they shouldn’t need to search any longer than two minutes.  90 percent said that searches longer than four minutes were totally unacceptable.  27 percent said that four-minute-plus searches were routine for their organizations.Jeremy Bentley, Chief Executive at Smartlogic, says: “This research shows that much of the work generated by most enterprises remains unlabeled and therefore invisible. The result is that a great deal of employee time is lost fruitlessly searching for information assets, many of which are never found, and the costs are huge. This and other studies have shown that this wasted labour can add up millions of dollars, pounds and euros in lost wages – equivalent to maybe 10% of the total salary bill for a large organisation. And in the end, most organisations are still failing to leverage their most valuable information assets.The Smartlogic research then turned towards specific industry segments to compare the efficiencies of search by industry.  The industries were graded against the following four criteria:Enterprise Search Effectiveness — a measure of how easy it is  find internal documents and filesInformation Categorization Effectiveness — a measure of how consistent the organization is in assigning tags and metadata to documentsFragmentation of Information Systems — a measure of how centralized information management in the organization is across departments.  Considers number of systems, databases and formats.Categorization and Search Progress and Investment — a measure of how the organization is attempting to improve the findability of their informationThe industry rankings are as follows.  The higher percentage is a better score and represents better efficiencies in the ability to locate information: The report notes that the more an industry tends to rely on unstructured rather than structured information, the lower their score and the more difficult it is to develop a program or system for searching their information. 49 percent – Extraction Industries41 percent – Law and Order / Emergency Services41 percent – Insurance and Financial Services40 percent – Education40 percent – Government39 percent – Healthcare37 percent – Manufacturing37 percent – Inforamtion and Research34 percent – Banking33 percent – Chemicals and Pharmaceuticals32 percent – Aerospace32 percent – Hi-tech and ITlast_img read more


Enterprise Businesses: Venture Capitalists Focus on Enterprise Software in 2013

Posted On Dec 17 2019 by

first_imgPalantir Technologies$56,120,000 Qualtrics Labs$70,000,000 Drilling Info$116,832,000 Internet Pipeline$71,435,100 Cloudera$64,677,100 Box, Inc.$125,000,200 Mark Heesen, president of NVCA, said that “We continue to see the impact of public policy on venture capital investment levels in very specific ways. Life sciences investment was suppressed for much of the year, particularly with first-time fundings, due in part to the impact of the regulatory and reimbursement environments, while clean tech investors began moving towards more capital efficient deals less dependent on government support. Simultaneously, investment in information technology flowed, as far fewer obstacles impeded success in those sectors.”In 2013, to take advantage of the current investment climate, enterprise-focused software businesses like SugarCRM and Alfresco are eyeing potential IPO’s.As an example of what VC’s are thinking, Promod Haque, venture capitalist at Norwest Venture Partner, said that in 2013 that they are excited about opportunities in health care IT, enterprise software, data networking, and ‘the infrastructure in general.’  The NVCA survey found that 61 percent of VS’s expect increased investments into business IT and a 57 percent increase to health-care IT.  On the other hand, NVCA also expects a drops of 61 percent drop in clean technology and 53 percent in medical device investments. GitHub$99,500,000 Businesses focused exclusively on consumers are losing favor with investors.  2013 is shaping up to be a year where businesses focused on enterprise software will do well.  Peter Cohan of Young Entrepreneur reports that consumer businesses like Facebook, Groupon, and Zygna were all well below their IPO first-day prices by 11 percent, 81 percent, and 75 percent, respectively.The top seven venture-funded enterprise software startups are shown in the chart below.  The total venture capital injected into these businesses in 2012 exceeded $600 million.  Data for the chart was supplied by the National Venture Capital Association and compiled by Marcus Wohlsen at Wired magazine.  The NVCA found that in 2012 venture capital investments across all sectors declined by 10 percent.  The year saw investments of over $26.5 billion in 3698 deals.   That’s the first time in three years that there was a decline in spending.  Industries like clean technology and life sciences saw the biggest declines, while software deals actually saw good gains.last_img read more


House panel would block NSF from building two new ships

Posted On Dec 1 2019 by

first_img“I know there are a number of underutilized research ships around the country,” Culberson told ScienceInsider after his panel approved a $56 billion bill that would fund NSF and several other federal agencies. “So I need to see evidence from NSF that they are fully utilizing the existing fleet.” Culberson was referring to the University-National Oceanographic Laboratory System (UNOLS), which operates a fleet of 17 ships belonging to NSF, the U.S. Navy, and several private institutions.Keeping them at seaNSF officials dispute his assessment. “That’s an unfortunate view, because we are not underutilized,” says Rick Murray, division director for ocean sciences at NSF in Arlington, Virginia. Although the rate varies by ship, he says, most UNOLS ships are at or near 100% usage.Ships can’t be operated 365 days a year, he notes, because of the need for routine maintenance, transit times, and the time needed to load and unload research equipment for each cruise. The typical ship spends 270 to 300 days at sea, although that number may be exceeded under special circumstances. And UNOLS eventually meets the needs of every scientist with a research grant that requires ship time, he adds, through a complicated process of matching scientists with the right vessel. The ships are not interchangeable; for example, the Atlantis is only used by those who want to deploy Alvin, its deep-diving submarine, and the Marcus Langseth is focused on seismic research.What Culberson may have been thinking about is how the fleet has been affected by years of tight budgets and rising costs. “Budgetary constraints across the Federal agencies, combined with escalating costs of new regulations, fuel, crew salaries and repairs, have led to a forced reduction in the utilization of ships to support ocean science projects,” a 2015 UNOLS report noted.Those fiscal realities have forced federal officials to reduce the size of the UNOLS fleet over the past several years but with no loss of capacity. Murray calls it “right-sizing,” that is, replacing older, less capable ships with fewer vessels that can do more science and are more efficient to operate.The new ships that NSF would build are called regional-class research vessels. They fall in the middle of a spectrum that ranges from larger ships that ply the oceans for weeks at a time and smaller ships that explore coastal waters. There is currently only one such regional-class vessel in the UNOLS fleet, operated by the University of Delaware, Newark. Oregon State University, Corvallis, has a contract with NSF to manage construction of the new ships, and would get to operate the first one. NSF would hold a competition for the right to operate the second and third ships, were they to be built.No strings attachedThe ships are part of an account that NSF uses to build large scientific facilities, like telescopes and ships. And although Culberson shrunk that account by removing the funding for the ships, he added $46 million to NSF’s $6 billion research account, which makes up the bulk of the agency’s budget. And NSF would have the freedom to spend the money across its six research directorates, unlike last year, when Culberson proposed growing the biology, computing, physical sciences, and engineering directorates at the expense of the social and geosciences.“You’ll notice that there is no directorate-level funding in the bill,” he says. “I’m a big believer of having the peer-review process go forward, unimpeded, without political pressure or influence from either side.”At the same time, Culberson warned NSF that it needs to do a better job of explaining to the public the value of each funded project. Some Republican legislators regularly poke fun at specific NSF grants they consider wasteful, frivolous, or politically motivated. And Culberson believes they are sometimes on target.“Of course, we’re human,” he says when asked whether he had any evidence that some scientists let their political views influence their research. “But we all have to do our best to follow the facts and objectively present the scientific evidence we see in the historical record, both in the geology of the Earth and the universe around us.” A congressional spending panel has rejected a request by the National Science Foundation (NSF) for $106 million to start building two new research vessels for the nation’s academic fleet. Yesterday’s action by an appropriations subcommittee in the U.S. House of Representatives puts the panel at odds with its Senate counterpart, which last month exceeded NSF’s request and backed construction of three vessels. A key lawmaker’s explanation of the House move also reveals a misunderstanding of the nature of the academic fleet and how it operates.The House panel, chaired by Representative John Culberson (R–TX), approved an overall budget for NSF of $7.406 billion. That figure is some $57 million below its current level and $103 million below what the Senate panel embraced. Both the Senate and House figures are below the president’s request for $7.564 billion in discretionary spending for the 2017 fiscal year that starts on 1 October. At the same time, the House bill adds $46 million to NSF’s current research account, which the Senate held steady. Legislators aren’t likely to work out their differences until after the November elections.The ocean research community had initially requested three ships, estimated to cost a total of $380 million. But NSF pared down that request to two, in line with a report by a National Academies of Sciences, Engineering, and Medicine panel, before submitting its 2017 budget last fall to the White House. Culberson thinks NSF shouldn’t have asked for any at this time.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)last_img read more


Vaccines that rob microbes of iron could fight food poisoning, UTIs

Posted On Dec 1 2019 by

first_imgYou’re probably not aware of it, but when you’re suffering from a bad case of food poisoning or another infection, bacteria are busy stealing iron from you. Many microbes use special chemicals to snatch away the metal, which they need to reproduce. But this need could be their downfall, according to new research. For the first time, two separate groups have developed candidate vaccines that protect against infection by targeting iron-scavenging molecules. The shots didn’t prevent disease in mice, but they did slow down infection, showing the concept might work.Iron is a hot commodity inside the human body. The metal is essential for producing energy and replicating DNA; it has a starring role in hemoglobin, the protein that carries oxygen inside red blood cells. Bacteria also need iron to grow and divide, and they have special molecules called siderophores that bind to the metal and rip it right out of the proteins in which it is ensconced. Siderophores then ferry the precious cargo back to the bacterial cell by binding to a specialized receptor.Scientists have tried to exploit this mechanism by devising vaccines that unleash antibodies against the receptors. A few have shown promise, but the receptors repel water and are insoluble, making the vaccine harder to manufacture. An alternative approach is to target the siderophores themselves. The problem is that siderophores aren’t naturally good at revving up the immune system, since they’re so small. To make them more visible to B cells and other immune responders, two groups of scientists decided to hook up synthesized siderophores to so-called carrier proteins, large proteins that the immune system views as “foreign,” and try the resulting conjugates as vaccines.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)A group at the University of Michigan in Ann Arbor designed a vaccine targeting the siderophores of Escherichia coli urinary tract infections, while a team at Massachusetts Institute of Technology and the University of California (UC), Irvine, took aim at a Salmonella strain that causes food poisoning. Each group immunized mice with their conjugate; several weeks later, they challenged the animals with a big dose of bacteria.As the researchers reported in a pair of papers in the Proceedings of the National Academy of Sciences this month, the siderophore shots didn’t prevent disease; vaccinated mice still developed infections, many of which were severe. But vaccinated mice had dramatically fewer bacteria in their bodies compared with mice that received a dose of the carrier protein alone. In the E. coli study, for instance, vaccinated mice had at least 10 times fewer E. coli in their urine and kidneys, which—along with their bladders—were less inflamed than those of control mice. In the Salmonella experiments, bacterial numbers were as much as 20,000-fold lower in the vaccinated mice and scientists also identified antibodies specific to the siderophores that seem responsible for the protection.These results are important, say the researchers, but they are still first steps. “It was kind of long shot, but it worked,” says Manuela Raffatellu, a microbiologist at UC Irvine and a senior author on the Salmonella study. “It’s certainly not ready for prime time,” concedes Harry Mobley, a bacteriologist who led the E. coli study at Michigan. Nevertheless, he’s “very excited about the finding.” Mobley hopes that a similar vaccine can be tested in humans 5 years from now. Because related species of disease-causing bacteria often produce chemically similar siderophores, a single vaccine might work against a variety of different bacteria, he says.Eric Skaar, a microbiologist at Vanderbilt University Medical Center in Nashville, Tennessee, who was not involved with the work, calls the findings “pretty impressive.” “Any time two different groups have very similar results using similar strategies, it really speaks to the robustness,” he says. The results provide an important proof of concept, adds James Johnson, an infectious disease physician at the Minneapolis Veterans Administration Health Care System in Minnesota. He says such vaccines could be an alternative to antibiotics, which are becoming increasingly ineffective and often wipe out good bacteria as well: “We really do need to push this line of investigation further because of the antibiotic resistance crisis we’re having now.”last_img read more


Our growing taste for shrimp is bad news for climate change

Posted On Dec 1 2019 by

first_imgSplit Second Stock/shutterstock.com Fishing boats are catching more shrimp and lobsters than ever before—and although that may be good news for your next visit to a seafood restaurant, it’s not so hot for climate change. The amount of carbon dioxide (CO2) emitted by fishing vessels rose 28% from 1990 to 2011, according to a new study, thanks largely to a greater haul of this premium seafood.The findings are especially alarming because, over the past 2 decades, some fishing boats have become more fuel efficient and buyouts of excess fishing vessels have decreased competition and distances traveled. But the additional emissions from shrimp and lobster fishing have outweighed those gains. Pulling nets through the water adds considerable drag and also requires lower speeds, both factors that drain fuel tanks quickly. Lobster fishing also takes a lot of diesel to place, check, and retrieve the traps. Despite the costs, demand has been rising. In 2011, the amount of crustaceans caught was 60% higher than in 1990—a greater increase than for any other type of seafood—the researchers report today in Nature Climate Change.All told, crustaceans account for 22% of the CO2 emissions from fishing, despite making up just 6% of all the tonnage landed. Given that fuel prices have decreased since 2008, the researchers expect that the trend has continued. The carbon intensity of lobster and wild-caught shrimp is less than most beef or lamb, they note. So surf still beats turf. But by far the most climate-friendly seafood is small pelagic fish, such as sardines, herrings, and anchovies.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*) By Erik StokstadApr. 2, 2018 , 1:25 PMcenter_img Our growing taste for shrimp is bad news for climate changelast_img read more


Line-ups: RB Salzburg v Napoli

Posted On Nov 30 2019 by

first_img Watch Serie A live in the UK on Premier Sports for just £11.99 per month including live LaLiga, Eredivisie, Scottish Cup Football and more. Visit: https://subscribe.premiersports.tv/ Napoli look to Dries Mertens, Hirving Lozano, but Kostas Manolas is injured and Lorenzo Insigne dropped against all-attack RB Salzburg and Erling Haaland. It kicks off at the Red Bull Arena at 20.00 UK time (19.00 GMT). You can follow all the build-up and action as it happens from this game and Inter-Borussia Dortmund on the LIVEBLOG. You can follow all the build-up and action as it happens from this game and Inter-Borussia Dortmund on the LIVEBLOG. The Partenopei have kept three consecutive clean sheets in all competition, but that included disappointing goalless draws with Torino and Genk. It’s remarkable considering the injury crisis in defence that has ruled out Faouzi Ghoulam, Elseid Hysaj, Nikola Maksimovic and Mario Rui. Kostas Manolas sustained a knock to the ribs during the 2-0 win over Verona at the weekend and is not moving comfortably, so it was decided not to risk him. Instead, 23-year-old Sebastiano Luperto makes his career Champions league debut and Giovanni Di Lorenzo is again re-routed to left-back. Piotr Zielinski and Jose Callejon take the wings, with Insigne again dropped to the bench after the Genk trip. Mertens is still only one goal away from Diego Armando Maradona’s tally in the Napoli jersey. His partner this time is not Arkadiusz Milik or Fernando Llorente, but the more agile Chucky Lozano, returning after a bruised ankle on international duty with Mexico. Napoli have already faced RB Salzburg in the Europa League Round of 16 last season and it was a tense affair, as while the Partenopei won the first leg 3-0 at home and took the early lead in Austria through Milik, they ended up losing 3-1 and only scraping through. Salzburg are arguably a much stronger team now and can count on 19-year-old sensation Erling Braut Haaland, the son of Alf-Inge Haaland, who scored a hat-trick in the 6-2 win over Genk. The Norwegian has 18 goals in 12 competitive games for his club this season, including four hat-tricks, so an average of a goal every 48 minutes. Another danger man is Dominik Szoboszlai, who will turn 19 on Friday and is the youngest player to have scored in the Champions League this season. Home advantage could be decisive, because RB Salzburg have won their last 13 home games in a row in all competition, since a 0-0 draw with Sturm Graz on March 10. They are unbeaten at home in all competition since November 2016, 1-0 against Admira Wacker in the Bundesliga. Their most recent European defeat here was 1-0 to Nice in the Europa League group stage on October 20, 2016. On the other hand, Napoli have not won a Champions League away fixture in three years, so a draw would probably qualify as a positive result here. They’ve won only one of their last seven European away games, 3-1 at FC Zurich, along with three draws and as many defeats. RB Salzburg: Stankovic; Kristensen, Ramalho, Wober, Ulmer; Daka, Junuzovic, Mwepu, Minamino; Hwang, Haaland Salzburg bench: Coronel, Ashimeru, Vallci, Onguene, Koita, Szoboszlai, Okugawa Napoli: Meret; Malcuit, Koulibaly, Luperto, Di Lorenzo; Callejon, Allan, Fabian Ruiz, Zielinski; Mertens, Lozano Napoli bench: Ospina, Elmas, Gaetano, Younes, Insigne, Milik, Llorente Ref: Turpin (FRA)last_img read more